Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 11/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032947 | 0.90 | AR (0.44) | ARTAS2R8IGF1RMCHR1 | |
| SCHEMBL8030958 | 0.88 | ELANE (0.46) | ARTAS2R8IGF1R | |
| SCHEMBL1773797 | 0.88 | MGLL (0.45) | ARTAS2R8IGF1RMCHR1 | |
| SCHEMBL8029473 | 0.88 | TAS2R8 (0.46) | ARTAS2R8 | |
| SCHEMBL12603161 | 0.88 | AR (0.45) | ARTAS2R8IGF1RMCHR1 | |
| SCHEMBL8027615 | 0.87 | AR (0.47) | ARTAS2R8IGF1RMCHR1 | |
| SCHEMBL12603154 | 0.86 | MCHR1 (0.50) | TAS2R8MCHR1 | |
| SCHEMBL12603129 | 0.86 | MCHR1 (0.42) | ARTAS2R8IGF1RMCHR1 | |
| SCHEMBL1773640 | 0.85 | AR (0.40) | ARTAS2R8IGF1RMCHR1 | |
| SCHEMBL12603147 | 0.85 | TAS2R8 (0.44) | ARTAS2R8IGF1RPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097997-A1 | SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |