SCHEMBL8033375

SCHEMBL8033375

CCCCCc1ccccc1C(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.51
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARA Q07869 2/20 0.47
PPARG P37231 1/20 0.47
EP300 Q09472 1/20 0.47
KAT2A Q92830 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT5 Q92993 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
CYSLTR2 Q9NS75 6/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31602282 0.98 LIPG (0.54) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL8093495 0.98 LIPG (0.54) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL963965 0.98 LIPG (0.54) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL9560320 0.98 LIPG (0.54) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL1332880 0.98 LIPG (0.54) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL3181025 0.95 TSHR (0.44) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL12711080 0.89 F7 (0.56) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL3180114 0.87 ALDH1A1 (0.45) PPARAPPARGTSHRTP53CYP3A4
SCHEMBL617126 0.85 LIPG (0.55) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL8087557 0.85 BID (0.48) LIPGBIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0174102-B1 POLYMERIZATION CATALYST, PRODUCTION AND USE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-04-19 EP claimed
JP-6263703-A None JP disclosed
CN-116462940-B Low-warpage antibacterial PET material and preparation method thereof 深圳市富恒新材料股份有限公司 2024-03-19 CN disclosed
CN-116462940-A Low-warpage antibacterial PET material and preparation method thereof 深圳市富恒新材料股份有限公司 2023-07-21 CN disclosed
CN-106608934-A Catalyst component used for olefin polymerization and preparation method and application thereof, catalyst system used for olefin polymerization and application thereof, and olefin polymerization method 中国石油化工股份有限公司 2017-05-03 CN disclosed
CN-1506355-A Diphenyl benzimidazole compound containing sulfonyl group and its prepn process, medicinal composition and use 中国医学科学院药物研究所 2004-06-23 CN disclosed
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
EP-0981588-A1 TOUGHENED GRAFTED POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-03-01 EP disclosed
WO-1998051755-A1 TOUGHENED GRAFTED POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed
JP-H06263703-A P-ACYLOXYBENZAMIDE DERIVATIVE, BLEACHING ACTIVATOR AND BLEACHING COMPOSITION CONTAINING THE SAME LION CORP 1994-09-20 JP disclosed
EP-0167919-B1 BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1993-05-05 EP disclosed
US-5151213-A Liquid crystal compounds and display elemints MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-09-29 US disclosed