Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032196 | 0.86 | PPARG (0.60) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8034331 | 0.85 | PPARG (0.57) | PPARGMAPTKMT2AMEN1PKM | |
| SCHEMBL8037846 | 0.85 | PPARG (0.57) | PPARGMAPTKMT2AMEN1PKM | |
| SCHEMBL8034144 | 0.84 | MAPT (0.66) | PPARGMAPTKMT2AMEN1PKM | |
| SCHEMBL4536851 | 0.84 | MAPT (0.54) | PPARGMAPTKMT2AMEN1PKM | |
| SCHEMBL4540776 | 0.83 | MAPT (0.63) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL4534800 | 0.82 | KMT2A (0.67) | MAPTKMT2AMEN1PKMMAPK1 | |
| SCHEMBL4542097 | 0.82 | PPARG (0.56) | PPARGMAPTKMT2AMEN1MAPK1 | |
| SCHEMBL4530973 | 0.81 | PPARG (0.54) | PPARGCYP1A2CYP3A4MAPTKMT2A | |
| SCHEMBL8041848 | 0.81 | MAPT (0.56) | PPARGMAPTKMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |