Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033972 | 0.86 | PPARG (0.57) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8038556 | 0.84 | PPARG (0.61) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8032177 | 0.84 | PPARG (0.60) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8034344 | 0.83 | PPARG (0.54) | PPARGHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4538730 | 0.83 | PPARG (0.57) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4537762 | 0.81 | PPARG (0.48) | PPARGHDAC1 | |
| SCHEMBL4540765 | 0.81 | MEN1 (0.52) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4538247 | 0.81 | PPARG (0.59) | PPARG | |
| SCHEMBL4537201 | 0.80 | PPARG (0.57) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8032490 | 0.79 | PPARG (0.55) | PPARGHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |