Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542097 | 0.89 | PPARG (0.56) | PPARGMAPTMAPK1RXFP1MEN1 | |
| SCHEMBL8035877 | 0.87 | PPARG (0.56) | PPARGMAPTMAPK1TAS1R3TAS1R1 | |
| SCHEMBL8032177 | 0.86 | PPARG (0.60) | PPARGTAS1R3TAS1R1 | |
| SCHEMBL8024491 | 0.85 | PPARG (0.56) | PPARGMAPTMAPK1TAS1R3TAS1R1 | |
| SCHEMBL8039661 | 0.85 | MAPT (0.50) | PPARGMAPTMAPK1RXFP1MEN1 | |
| SCHEMBL8033972 | 0.85 | PPARG (0.57) | PPARGMAPTMAPK1RXFP1MEN1 | |
| SCHEMBL4540776 | 0.83 | MAPT (0.63) | MAPTMAPK1RXFP1MEN1KMT2A | |
| SCHEMBL8035392 | 0.82 | PPARG (0.53) | PPARGMAPTMAPK1MEN1KMT2A | |
| SCHEMBL8036315 | 0.82 | MEN1 (0.57) | PPARGMAPTMAPK1MEN1KMT2A | |
| SCHEMBL4530973 | 0.81 | PPARG (0.54) | PPARGMAPTMAPK1RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |