Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045407 | 0.89 | KCNH2 (0.39) | KCNH2EPHX2CTSKNAAAHCRTR1 | |
| SCHEMBL8048334 | 0.88 | KCNH2 (0.40) | KCNH2EPHX2CTSKNAAAHCRTR1 | |
| SCHEMBL8045510 | 0.88 | EPHX2 (0.36) | KCNH2EPHX2CTSKNAAAGRM2 | |
| SCHEMBL8049218 | 0.87 | CHRM4 (0.35) | CHRM2CHRM5GRM2CHRM1CHRM3 | |
| SCHEMBL8431668 | 0.87 | CTSK (0.36) | EPHX2CTSKNAAAHCRTR1HCRTR2 | |
| SCHEMBL8046030 | 0.87 | EPHX2 (0.37) | KCNH2EPHX2CTSKNAAAHCRTR1 | |
| SCHEMBL8046214 | 0.86 | KCNH2 (0.43) | KCNH2EPHX2HCRTR1HCRTR2CHRM2 | |
| SCHEMBL8045381 | 0.86 | CHRM2 (0.32) | CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8046723 | 0.84 | KIF11 (0.38) | — | |
| SCHEMBL8034560 | 0.81 | SLC6A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |