Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030787 | 0.92 | RXFP1 (0.57) | RXFP1TP53SMN1; SMN2THRBMAPT | |
| SCHEMBL8019460 | 0.85 | HTR6 (0.60) | RXFP1TP53THRBMAPTHTR6 | |
| SCHEMBL667284 | 0.79 | THRB (0.79) | RXFP1TP53SMN1; SMN2THRBMAPT | |
| SCHEMBL8019463 | 0.79 | HPGD (0.53) | RXFP1TP53MAPTHTR6POLB | |
| SCHEMBL16691052 | 0.77 | THRB (0.75) | RXFP1TP53SMN1; SMN2THRBMAPT | |
| SCHEMBL8018278 | 0.77 | HPGD (0.60) | RXFP1TP53THRBMAPTHTR6 | |
| SCHEMBL8030786 | 0.77 | RXFP1 (0.65) | RXFP1TP53THRBMAPTHTR6 | |
| SCHEMBL8028875 | 0.77 | HTR6 (0.61) | RXFP1TP53MAPTHTR6POLB | |
| SCHEMBL16691103 | 0.74 | THRB (0.71) | RXFP1TP53SMN1; SMN2THRBMAPT | |
| SCHEMBL10123256 | 0.74 | THRB (0.64) | RXFP1TP53THRBMAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093934-A2 | SUBSTITUTED 3-SULPHONYL-[1,2,3]TRIAZOLO [1,5-A]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, MEDICINAL SUBSTANCE, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION AND METHODS FOR THE PRODUCTION THEREOF | ALLA CHEM, LLC (US) | 2009-07-30 | — | — | WO | disclosed |