SCHEMBL8034098

SCHEMBL8034098

Cc1cccc(N(C)C(=O)COc2cccc(N(CC(=O)N(C)c3ccccc3)C(=O)CN)c2)c1C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.46
MEN1 O00255 6/20 0.46
KDM4E B2RXH2 3/20 0.41
MLYCD O95822 2/20 0.41
NOTUM Q6P988 1/20 0.38
MAPK1 P28482 1/20 0.37
NTSR1 P30989 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NOD2 Q9HC29 1/20 0.37
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 2/20 0.36
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8031968 0.94 KMT2A (0.43) KMT2AMEN1KDM4EMLYCDNOTUM
SCHEMBL8030133 0.86 ALDH1A1 (0.45) KMT2AMEN1KDM4EMLYCDMAPK1
SCHEMBL27523449 0.86 KMT2A (0.47) KMT2AMEN1KDM4EMLYCDNOTUM
SCHEMBL8033749 0.86 MLYCD (0.43) KMT2AMEN1KDM4EMLYCDMAPK1
SCHEMBL8030265 0.86 KMT2A (0.43) KMT2AMEN1KDM4EMLYCDMAPK1
SCHEMBL8031976 0.83 ALDH1A1 (0.47) KMT2AMEN1KDM4EMLYCDMAPK1
SCHEMBL8030044 0.83 MLYCD (0.43) KMT2AMEN1KDM4EMLYCDMAPK1
SCHEMBL27487708 0.83 MLYCD (0.43) KMT2AMEN1KDM4EMLYCDMAPK1
SCHEMBL9134211 0.82 TSHR (0.43) KDM4EMLYCDMAPK1SMN1; SMN2ALDH1A1
SCHEMBL8034030 0.81 KMT2A (0.45) KMT2AMEN1KDM4EMLYCDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985660-A1 AMINOPHENOL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2000-03-15 EP disclosed