Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031968 | 0.88 | KMT2A (0.43) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8020728 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8034098 | 0.86 | KMT2A (0.46) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8032129 | 0.85 | KMT2A (0.44) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8033876 | 0.85 | KMT2A (0.40) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8030265 | 0.84 | KMT2A (0.43) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8033749 | 0.84 | MLYCD (0.43) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8828076 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL8031976 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPK1NTSR1HTT | |
| SCHEMBL8030044 | 0.83 | MLYCD (0.43) | ALDH1A1KMT2AMAPK1NTSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |