Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.56 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.56 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13683460 | 0.87 | SAT1 (0.48) | GNAI3GNAO1GNAI1SAT1SIGMAR1 | |
| SCHEMBL19700576 | 0.83 | SAT1 (0.41) | GNAI3GNAO1GNAI1SAT1SIGMAR1 | |
| SCHEMBL8048307 | 0.82 | ADH1B (0.42) | GNAI3GNAO1GNAI1SAT1SIGMAR1 | |
| SCHEMBL13772115 | 0.79 | GNAO1 (0.70) | GNAI3GNAO1GNAI1PRMT5WDR77 | |
| SCHEMBL5963013 | 0.79 | GNAI3 (0.75) | GNAI3GNAO1GNAI1PRMT5WDR77 | |
| SCHEMBL21987001 | 0.78 | GNAI3 (0.55) | GNAI3GNAO1GNAI1PRMT5WDR77 | |
| SCHEMBL15172593 | 0.78 | GNAI3 (0.58) | GNAI3GNAO1GNAI1PRMT5WDR77 | |
| SCHEMBL669897 | 0.77 | GNAI3 (0.56) | GNAI3GNAO1GNAI1PRMT5WDR77 | |
| SCHEMBL7328368 | 0.76 | GNAO1 (0.83) | GNAI3GNAO1GNAI1PRMT5WDR77 | |
| SCHEMBL23919173 | 0.76 | DPP4 (0.38) | GNAI3GNAO1GNAI1SAT1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071707-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2009-06-11 | — | — | WO | disclosed |