SCHEMBL8034260

SCHEMBL8034260

CS(=O)(=O)n1c(S)nc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
ALDH3A1 P30838 6/20 0.46
NOD1 Q9Y239 6/20 0.45
CXCL8 P10145 4/20 0.45
NOD2 Q9HC29 2/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
KDM4E B2RXH2 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL990493 0.82 NOD1 (0.45) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL11327144 0.81 NOD1 (0.44) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL9320052 0.81 NOD1 (0.44) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL14356320 0.79 NOD1 (0.67) ALDH3A1NOD1CXCL8NOD2LMNA
SCHEMBL7837246 0.79 SMN1; SMN2 (0.56) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL4873241 0.79 NOD1 (0.66) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL8042793 0.78 ALDH3A1 (0.74) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL5859680 0.75 MEN1 (0.50) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL5858877 0.75 CYP1A2 (0.48) SMN1; SMN2ALDH3A1NOD1CXCL8NOD2
SCHEMBL16376073 0.73 TDP1 (0.58) SMN1; SMN2NOD1LMNAGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983316-A1 A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE Duslo, a.s. Sal'a (SK) 2000-03-08 EP disclosed
WO-1998046673-A1 A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE DUSLO, A.S. S^¿ALA (SK) 1998-10-22 WO disclosed