SCHEMBL990493

SCHEMBL990493

O=S(=O)(O)n1c(S)nc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 6/20 0.45
CXCL8 P10145 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
POLB P06746 1/20 0.44
ALDH3A1 P30838 5/20 0.43
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HTT P42858 3/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
NOD2 Q9HC29 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320052 0.98 NOD1 (0.44) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL11327144 0.98 NOD1 (0.44) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL8034260 0.82 SMN1; SMN2 (0.49) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL14356320 0.79 NOD1 (0.67) NOD1CXCL8ALDH3A1ALDH1A1HTT
SCHEMBL28063595 0.79 SMN1; SMN2 (0.52) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL573404 0.76 KDM4E (0.53) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL9394279 0.75 NOD1 (0.42) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL6519743 0.75 L3MBTL1 (0.52) SMN1; SMN2POLBALDH3A1ALDH1A1HTT
SCHEMBL8042793 0.74 ALDH3A1 (0.74) NOD1CXCL8SMN1; SMN2POLBALDH3A1
SCHEMBL9486088 0.71 NPC1 (0.51) SMN1; SMN2POLBALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9428545-B2 Process for isolation of plasma or serum proteins THERAPURE BIOPHARMA INC. (CA) 2016-08-30 US claimed
US-20160009757-A1 PROCESS FOR ISOLATION OF PLASMA OR SERUM PROTEINS THERAPURE BIOPHARMA INC. (CA) 2016-01-14 US claimed
EP-1765866-B1 ISOLATION OF PLASMA OR SERUM PROTEINS THERAPURE BIOPHARMA INC (CA) 2014-01-08 EP claimed
CN-113559105-A Treatment of resistant acne 维奥姆治疗有限公司 2021-10-29 CN disclosed
CN-113164589-A Compositions and methods for modulating monocyte and macrophage inflammatory phenotype and immunotherapy uses thereof 维西欧制药公司 2021-07-23 CN disclosed
CN-106163526-B Treatment of resistant acne 维奥姆治疗有限公司 2021-07-23 CN disclosed
CN-113164379-A Biodegradable lipids for delivery of active agents 阿尔尼拉姆医药品有限公司 2021-07-23 CN disclosed
EP-2632562-B1 METHODS FOR CAPTURING VIRUS LIKE PARTICLES FROM PLANTS USING EXPANDED BED CHROMATOGRAPHY PHILIP MORRIS PRODUCTS SA (CH) 2020-08-05 EP disclosed
US-20170282095-A1 Process For Isolation of Plasma or Serum Proteins THERAPURE BIOPHARMA INC. (CA) 2017-10-05 US disclosed
US-9624260-B2 Process for isolation of plasma or serum proteins THERAPURE BIOPHARMA INC. (CA) 2017-04-18 US disclosed
EP-3127916-A1 ISOLATION OF PLASMA OR SERUM PROTEINS Therapure Biopharma Inc. (CA) 2017-02-08 EP disclosed
US-4767692-A NUCLEATING AGENT WITH UREA AND HYDRAZIDE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1988-08-30 US disclosed
US-4755448-A Having layer containing hydrazine derivative and tertiary amine salt of acid polymer FUJI PHOTO FILM CO., LTD. (JP) 1988-07-05 US disclosed
EP-0267598-A2 Superhigh contrast negative-type silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP disclosed
US-4725532-A CONTAINING HYDRAZIDE DERIVATIVE, CATIONIC DYE AND ASCORBIC ACID FUJI PHOTO FILM CO., LTD. (JP) 1988-02-16 US disclosed
US-4722884-A LARGER THAN AVERAGE SILVER IODIDE CONTENT IN SURFACE PART OF GRAIN; HYDRAZIDE IN ONE OF LAYERS FUJI PHOTO FILM CO., LTD. (JP) 1988-02-02 US disclosed
US-4699873-A HYDRAZINE DERIVATIVE COMPOUND AND DISULFIDE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1987-10-13 US disclosed
US-4681836-A RHODIUM SALT, HYDRAZINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
EP-0196626-A2 Silver halide photographic material and method for forming an ultrahigh contrast negative image therewith FUJI PHOTO FILM CO., LTD. (JP) 1986-10-08 EP disclosed
US-4332878-A USING A HYDROQUINONE DERIVATIVE IN THE SILVER HALIDE EMULSION LAYER AND DEVELOPING IN THE PRESENCE OF A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-01 US disclosed