Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.52 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940208 | 0.84 | LMNA (0.49) | ALDH1A1LMNACYP2C9TYRALOX15 | |
| SCHEMBL7940345 | 0.84 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1RARBRARGRARA | |
| SCHEMBL8030253 | 0.80 | CYP2C9 (0.41) | NR1I2ALDH1A1LMNACYP2C9TYR | |
| SCHEMBL18587755 | 0.77 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1RARBRARGRARA | |
| SCHEMBL7942429 | 0.76 | GAA (0.45) | HSP90AA1HSP90AB1NR1I2ALDH1A1LMNA | |
| SCHEMBL7942288 | 0.75 | HPGD (0.53) | HSP90AA1HSP90AB1RARBRARGRARA | |
| SCHEMBL12301909 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL7941478 | 0.73 | CA2 (0.44) | NR1H4ALDH1A1 | |
| SCHEMBL13078326 | 0.72 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1RARBRARGRARA | |
| SCHEMBL7942516 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNACYP2C9TYRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075159-A | USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-13 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |