Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599622 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL5384353 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL1813924 | 0.75 | HPGD (0.50) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL22356176 | 0.75 | NOS2 (0.44) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL8626242 | 0.75 | HPGD (0.50) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL8627456 | 0.75 | HPGD (0.50) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL22356162 | 0.75 | NOS2 (0.44) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL22480301 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL845360 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL17361182 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | claimed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | claimed |
| US-6057324-A | HAVE GPIIB/IIIA RECEPTOR ANTAGONIZING ACTIVITY AND ARE USEFUL FOR AMELIORATING ISCHEMIC CARDIAC DISORDERS, FOR AMELIORATING CEREBROVASCULAR DISORDERS, AND FOR AMELIORATING PERIPHERAL ARTERY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0905129-A1 | SUBSTITUTED AMIDINOBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |