Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888316 | 0.88 | PIK3C3 (0.38) | PIK3C3HSP90AA1PIK3CDCXCR4PDE4A | |
| SCHEMBL803399 | 0.79 | KDM4E (0.40) | CXCR4 | |
| SCHEMBL803465 | 0.79 | GABRA1 (0.41) | — | |
| SCHEMBL28502029 | 0.77 | GBA1 (0.44) | CXCR4 | |
| SCHEMBL803096 | 0.76 | CYP19A1 (0.49) | — | |
| SCHEMBL803470 | 0.75 | MAP4K4 (0.35) | PIK3C3PIK3CD | |
| SCHEMBL803403 | 0.74 | KDM4E (0.36) | CXCR4 | |
| SCHEMBL16615298 | 0.73 | CXCR4 (0.37) | HSP90AA1CXCR4 | |
| SCHEMBL803080 | 0.72 | PDE2A (0.37) | CXCR4 | |
| SCHEMBL803111 | 0.71 | HSP90AA1 (0.38) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | PIK3C3 4639/4885HSP90AA1 2767/4885PIK3CD 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.