Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097183 | 0.80 | HSP90AA1 (0.59) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL3382683 | 0.78 | HSP90AA1 (0.58) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL2884972 | 0.78 | HSP90AA1 (0.58) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL9860748 | 0.76 | KDM4E (0.59) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL169519 | 0.76 | LMNA (0.50) | LMNAKDM4EMAPTHSP90AA1L3MBTL1 | |
| SCHEMBL1149641 | 0.76 | L3MBTL1 (0.61) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL8654916 | 0.76 | CCR1 (0.61) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL9860869 | 0.76 | LMNA (0.50) | LMNAKDM4EMAPTNR4A2HSP90AA1 | |
| SCHEMBL5473648 | 0.72 | HSP90AA1 (0.62) | LMNAKDM4EMAPTHSP90AA1L3MBTL1 | |
| SCHEMBL8410414 | 0.72 | SYK (0.59) | LMNAEGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984909-A1 | USE OF A RHODIUM CATALYST FOR HYDROAMINATION AND/OR OXIDATIVE AMINATION OF ARYL-SUBSTITUTED OLEFINS AND METHOD FOR PRODUCING A 2-ARYL VINYL AMINE | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-03-15 | — | — | EP | claimed |
| WO-1998054115-A1 | USE OF A RHODIUM CATALYST FOR HYDROAMINATION AND/OR OXIDATIVE AMINATION OF ARYL-SUBSTITUTED OLEFINS AND METHOD FOR PRODUCING A 2-ARYL VINYL AMINE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & (DE) | 1998-12-03 | — | — | WO | claimed |
| EP-0984909-A1 | USE OF A RHODIUM CATALYST FOR HYDROAMINATION AND/OR OXIDATIVE AMINATION OF ARYL-SUBSTITUTED OLEFINS AND METHOD FOR PRODUCING A 2-ARYL VINYL AMINE | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054115-A1 | USE OF A RHODIUM CATALYST FOR HYDROAMINATION AND/OR OXIDATIVE AMINATION OF ARYL-SUBSTITUTED OLEFINS AND METHOD FOR PRODUCING A 2-ARYL VINYL AMINE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & (DE) | 1998-12-03 | — | — | WO | disclosed |