SCHEMBL8035484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6288593	0.83	ALDH1A1 (0.50)	ALDH1A1CYP1A2TAAR1CYP3A4TDP1
	SCHEMBL11664569	0.82	TDP1 (0.53)	ALDH1A1CYP1A2CYP3A4TDP1HSD17B10
	SCHEMBL230096	0.82	TDP1 (0.53)	ALDH1A1CYP1A2CYP3A4TDP1HSD17B10
	Phosphine SCHEMBL21463026	0.79	TDP1 (0.50)	ALDH1A1CYP1A2CYP3A4TDP1CA1
	SCHEMBL28788167	0.79	TDP1 (0.50)	ALDH1A1CYP1A2CYP3A4TDP1CA1
	SCHEMBL11655670	0.79	TDP1 (0.50)	ALDH1A1CYP1A2CYP3A4TDP1CA1
	SCHEMBL29009366	0.79	TDP1 (0.50)	ALDH1A1CYP1A2CYP3A4TDP1CA1
	SCHEMBL8035535	0.79	ALDH1A1 (0.45)	ALDH1A1CYP1A2TAAR1CYP3A4TDP1
	Biphenyl SCHEMBL27646937	0.78	ALDH1A1 (0.69)	ALDH1A1CYP1A2TAAR1CYP3A4TDP1
	SCHEMBL2606103	0.77	MAOA (0.44)	ALDH1A1CYP1A2CYP3A4TDP1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.