SCHEMBL8035535

SCHEMBL8035535

ClP(c1cc(-c2ccccc2)cc(-c2ccccc2)c1)c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
CYP1A2 P05177 1/20 0.40
CRHBP P24387 2/20 0.38
CRHR2 Q13324 2/20 0.38
EGFR P00533 1/20 0.36
MAOA P21397 1/20 0.36
KMO O15229 1/20 0.35
ESR2 Q92731 1/20 0.35
PTGER1 P34995 1/20 0.35
PTGER4 P35408 1/20 0.35
PTGER3 P43115 1/20 0.35
PTGER2 P43116 1/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPK1 P28482 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NOTUM Q6P988 1/20 0.35
MMP3 P08254 1/20 0.35
BCL2L1 Q07817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2606103 0.83 MAOA (0.44) ALDH1A1CYP1A2MAOAKMOESR2
SCHEMBL8035484 0.79 ALDH1A1 (0.50) ALDH1A1CYP1A2ESR2CYP3A4TDP1
SCHEMBL8452262 0.78 ALDH1A1 (0.75) ALDH1A1CYP1A2CRHBPCRHR2EGFR
SCHEMBL4332773 0.78 ALDH1A1 (0.75) ALDH1A1CYP1A2CRHBPCRHR2EGFR
SCHEMBL481505 0.78 ALDH1A1 (0.75) ALDH1A1CYP1A2CRHBPCRHR2EGFR
SCHEMBL19968463 0.75 ALDH1A1 (0.45) ALDH1A1CYP1A2CRHBPCRHR2EGFR
SCHEMBL8033162 0.75 BACE1 (0.39) ALDH1A1MAPK1HSD17B10BCL2L1ALOX5
SCHEMBL5321294 0.74 ALDH1A1 (0.69) ALDH1A1CYP1A2CRHBPCRHR2EGFR
SCHEMBL29554408 0.74 ALDH1A1 (0.69) ALDH1A1CYP1A2CRHBPCRHR2EGFR
SCHEMBL5130299 0.74 ALDH1A1 (0.69) ALDH1A1CYP1A2CRHBPCRHR2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
CN-107548385-B Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-21 CN disclosed
CN-113896607-A Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
CN-107592863-B Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-09-10 CN disclosed
CN-107567355-B Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-6084133-A REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY KANKYO KAGAKU CENTER CO., LTD. (JP) 2000-07-04 US disclosed