Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633333 | 0.87 | SMN1; SMN2 (0.56) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8050248 | 0.84 | SMN1; SMN2 (0.48) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11140576 | 0.82 | SMN1; SMN2 (0.49) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8044856 | 0.82 | OPRM1 (0.48) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8049892 | 0.82 | OPRM1 (0.48) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27899326 | 0.81 | KIF11 (0.44) | CYP3A4TDP1 | |
| SCHEMBL31534031 | 0.81 | SMN1; SMN2 (0.45) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8046235 | 0.80 | OPRM1 (0.49) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1POLB | |
| Bromide SCHEMBL1634340 | 0.80 | KIF11 (0.43) | CYP3A4TDP1 | |
| SCHEMBL27577126 | 0.80 | KIF11 (0.46) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |