Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044856 | 1.00 | OPRM1 (0.48) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8046235 | 0.99 | OPRM1 (0.49) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL7830375 | 0.95 | OPRM1 (0.50) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8047298 | 0.93 | OPRM1 (0.44) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8046383 | 0.90 | CYP4F2 (0.40) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL7826967 | 0.89 | KCNA3 (0.52) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8035567 | 0.88 | CA12 (0.40) | OPRM1KCNA3CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL8035702 | 0.88 | SMN1; SMN2 (0.40) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8047345 | 0.88 | KCNA3 (0.40) | OPRM1KCNA3SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8053206 | 0.87 | FAAH (0.44) | OPRM1KCNA3CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |