Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035613 | 0.88 | S1PR1 (0.54) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8025544 | 0.85 | ALDH1A1 (0.49) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8035621 | 0.84 | ATM (0.48) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8025540 | 0.84 | SMN1; SMN2 (0.48) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8040248 | 0.83 | MTNR1A (0.52) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8037334 | 0.83 | S1PR1 (0.43) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8039098 | 0.83 | HPGD (0.48) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8039086 | 0.82 | MTNR1A (0.47) | S1PR1CTSVCTSLSMPD1HDAC1 | |
| SCHEMBL8037331 | 0.81 | MTNR1A (0.46) | S1PR1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL8025483 | 0.81 | MEN1 (0.46) | S1PR1CTSVCTSLSMPD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |