Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isovanillin SCHEMBL8035679 | 1.00 | ALDH1A1 (0.53) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| Cyclohexylamine SCHEMBL8025659 | 0.89 | GRIK1 (0.40) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| Cyclohexylamine SCHEMBL8025661 | 0.89 | GRIK1 (0.40) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| Isovanillin SCHEMBL8041267 | 0.89 | ALDH1A1 (0.48) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| Isovanillin SCHEMBL8041270 | 0.89 | ALDH1A1 (0.48) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| Isovanillin SCHEMBL7801472 | 0.89 | ALDH1A1 (0.58) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| Isovanillin SCHEMBL7799829 | 0.88 | ALDH1A1 (0.69) | ALDH1A1AOX1KMT2ATRIM24HPGD | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.82 | ALDH5A1 (0.41) | ALDH1A1KMT2AALDH5A1ABATGRIK1 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.82 | ALDH5A1 (0.41) | ALDH1A1KMT2AALDH5A1ABATGRIK1 | |
| 3-Hydroxybenzaldehyde SCHEMBL8039109 | 0.81 | KYNU (0.40) | KMT2ATDP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |