Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535196 | 0.89 | PPARG (0.72) | PPARGRORCKMT2AHTT | |
| SCHEMBL2161614 | 0.89 | PPARG (0.65) | PPARGRAB9ARORCHDAC1HDAC6 | |
| SCHEMBL8039631 | 0.88 | PPARG (0.68) | PPARGRORCALDH1A1HSD17B10 | |
| SCHEMBL31072749 | 0.87 | PPARG (0.52) | PPARGRAB9ARORCHDAC1HDAC6 | |
| SCHEMBL29343406 | 0.87 | PPARG (0.52) | PPARGRAB9ARORCHDAC1HDAC6 | |
| SCHEMBL8025911 | 0.86 | KDM4E (0.70) | PPARGRAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL6172342 | 0.85 | PPARG (0.54) | PPARGRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL29343405 | 0.84 | THRB (0.52) | PPARGRORCHSD17B10 | |
| SCHEMBL4570712 | 0.81 | PPARG (0.68) | PPARGRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL31072768 | 0.81 | PPARG (0.55) | PPARGRORCHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |