Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.68 |
| ▸ | CCR2 | P41597 | 2/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035707 | 0.88 | PPARG (0.64) | PPARGRORCALDH1A1HSD17B10 | |
| SCHEMBL8036225 | 0.88 | PPARG (0.65) | PPARGRORCALDH1A1 | |
| SCHEMBL31072768 | 0.87 | PPARG (0.55) | PPARGRORCALDH1A1TNFHSD17B10 | |
| SCHEMBL29342745 | 0.87 | PPARG (0.55) | PPARGRORCALDH1A1TNFHSD17B10 | |
| SCHEMBL31072749 | 0.85 | PPARG (0.52) | PPARGRORCALDH1A1HSD17B10 | |
| SCHEMBL29343406 | 0.85 | PPARG (0.52) | PPARGRORCALDH1A1HSD17B10 | |
| SCHEMBL4535196 | 0.85 | PPARG (0.72) | PPARGCCR2RORC | |
| SCHEMBL8025849 | 0.84 | THRB (0.65) | PPARGCCR2ALDH1A1HSD17B10 | |
| SCHEMBL29343405 | 0.82 | THRB (0.52) | PPARGCCR2RORCHSD17B10 | |
| SCHEMBL2161614 | 0.82 | PPARG (0.65) | PPARGRORCALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |