Cyclohexylamine

Cyclohexylamine

SCHEMBL8035751

NC1CCCCC1.NCC(N)C(=O)O.O=Cc1ccccc1Br

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.39
MAPT P10636 1/20 0.34
PPARG P37231 2/20 0.34
PPARA Q07869 2/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
ALPI P09923 1/20 0.33
PKM P14618 1/20 0.33
PTGS1 P23219 1/20 0.33
XIAP P98170 1/20 0.33
SLC7A5 Q01650 1/20 0.33
GRIK1 P39086 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
SRC P12931 1/20 0.33
HSD11B1 P28845 1/20 0.33
DPEP1 P16444 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL8035749 1.00 KIF11 (0.39) KIF11MAPTPPARGPPARAKMT2A
Lysine SCHEMBL8039335 0.88 GSR (0.43) KIF11KMT2A
Lysine SCHEMBL8039338 0.88 GSR (0.43) KIF11KMT2A
Cyclohexylamine SCHEMBL7802530 0.86 MAPT (0.37) MAPTKMT2AMEN1LMNACYP1A2
Cyclohexylamine SCHEMBL8036004 0.86 NPC1 (0.40) KIF11MAPTPPARGPPARAKMT2A
Cyclohexylamine SCHEMBL8036007 0.86 NPC1 (0.40) KIF11MAPTPPARGPPARAKMT2A
Cyclohexylamine SCHEMBL8039051 0.84 GRIK1 (0.46) KIF11PPARGPPARAKMT2AMEN1
Cyclohexylamine SCHEMBL8039053 0.84 GRIK1 (0.46) KIF11PPARGPPARAKMT2AMEN1
Benzaldehyde SCHEMBL8035694 0.84 KIF11 (0.42) KIF11PPARGPPARAKMT2AMEN1
Cyclohexylamine SCHEMBL7802599 0.83 KMT2A (0.42) MAPTKMT2AMEN1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed