Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8036007 | 1.00 | NPC1 (0.40) | NPC1MAPTRAB9ASMN1; SMN2KIF11 | |
| Lysine SCHEMBL8035193 | 0.89 | GSR (0.43) | NPC1MAPTRAB9ASMN1; SMN2KIF11 | |
| Lysine SCHEMBL8035194 | 0.89 | GSR (0.43) | NPC1MAPTRAB9ASMN1; SMN2KIF11 | |
| Cyclohexylamine SCHEMBL7801529 | 0.86 | NPC1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2C3AR1 | |
| Cyclohexylamine SCHEMBL8035749 | 0.86 | KIF11 (0.39) | MAPTKIF11HPGDPPARGPPARA | |
| Cyclohexylamine SCHEMBL8035751 | 0.86 | KIF11 (0.39) | MAPTKIF11HPGDPPARGPPARA | |
| Cyclohexylamine SCHEMBL8041278 | 0.85 | EPHX2 (0.33) | KIF11PPARGPPARAGRIK1 | |
| Cyclohexylamine SCHEMBL8041276 | 0.85 | EPHX2 (0.33) | KIF11PPARGPPARAGRIK1 | |
| Cyclohexylamine SCHEMBL8039051 | 0.84 | GRIK1 (0.46) | KIF11ALDH1A1HPGDEPHX1PPARG | |
| Cyclohexylamine SCHEMBL8039053 | 0.84 | GRIK1 (0.46) | KIF11ALDH1A1HPGDEPHX1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |