Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALPI | P09923 | 2/20 | 0.57 |
| ▸ | ALPG | P10696 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CUL4A | Q13619 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637378 | 0.78 | MAOA (0.52) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL6002101 | 0.75 | CUL4A (0.54) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL6001543 | 0.75 | CUL4A (0.54) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL5541064 | 0.75 | MAOA (0.63) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL995285 | 0.73 | MAPT (0.47) | MAOAMAOBMAPTALPIALPG | |
| Tioxolone SCHEMBL36433 | 0.73 | MAOA (1.00) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL2056163 | 0.73 | MAOA (0.61) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL995283 | 0.73 | MAPT (0.47) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL10397843 | 0.71 | MAPT (0.49) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL3802319 | 0.69 | MAOA (0.58) | MAOAMAOBMAPTALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832054-B1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 2000-12-27 | — | — | EP | disclosed |
| US-6063360-A | USEFUL AS CONTRAST AGENT FOR OVERHAUSER MAGNETIC RESONACE IMAGING | NYCOMED IMAGING A/S (NO) | 2000-05-16 | — | — | US | disclosed |
| EP-0662004-B1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996039367-A1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING A/S (NO) | 1996-12-12 | — | — | WO | disclosed |
| US-5530140-A | Free radicals | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |
| US-5435991-A | Use of persistent heterocyclic free-radicals in magnetic resonance imaging | NYCOMED INNOVATION AB (SE) | 1995-07-25 | — | — | US | disclosed |
| EP-0662004-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | Nycomed Innovation AB (SE) | 1995-07-12 | — | — | EP | disclosed |
| WO-1993002711-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1993-02-18 | — | — | WO | disclosed |