Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 5/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALPI | P09923 | 2/20 | 0.53 |
| ▸ | ALPG | P10696 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24091291 | 0.84 | MAPT (0.60) | CUL4AMAOAMAOBMAPTALPI | |
| SCHEMBL6002101 | 0.78 | CUL4A (0.54) | CUL4AMAOAMAOBMAPTALPI | |
| SCHEMBL8035971 | 0.75 | MAOA (0.57) | CUL4AMAOAMAOBMAPTALPI | |
| SCHEMBL10397843 | 0.74 | MAPT (0.49) | CUL4AMAOAMAOBMAPTALPI | |
| SCHEMBL996615 | 0.74 | CA9 (0.50) | CUL4AMAOAMAOBMAPTALPI | |
| SCHEMBL15572762 | 0.71 | CUL4A (1.00) | CUL4AMAOAMAOBMAPTALPI | |
| Tioxolone SCHEMBL36433 | 0.69 | MAOA (1.00) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL2101251 | 0.69 | MAPT (0.72) | MAOAMAOBMAPTALPIALPG | |
| Tioxolone SCHEMBL29427713 | 0.69 | MAOA (1.00) | MAOAMAOBMAPTALPIALPG | |
| SCHEMBL30273047 | 0.69 | MAPT (0.72) | MAOAMAOBMAPTALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060234987-A1 | Neuroprotective benzo 1 3 oxathiol 2 ones | JAQUITH JAMES B | 2006-10-19 | — | — | US | claimed |
| US-20210379060-A1 | SPT5 INHIBITORS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379060-A1 | SPT5 INHIBITORS AND USES THEREOF | SUPT16H, SPTLC1, MED25 | CUL4A 2717/4885MAOA 3679/4885MAOB 3135/4885 |
| US-20060234987-A1 | Neuroprotective benzo 1 3 oxathiol 2 ones | NLN, SMN1; SMN2, TXN2 | CUL4A 1534/4885MAOA 1236/4885MAOB 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.