Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
| ▸ | CTSH | P09668 | 2/20 | 0.30 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.30 |
| ▸ | DPEP1 | P16444 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8041278 | 1.00 | EPHX2 (0.33) | EPHX2KIF11GRIK1PPARGPPARA | |
| Lysine SCHEMBL8035763 | 0.89 | GSR (0.43) | CTSLCTSBCTSHCTSSCTSK | |
| Lysine SCHEMBL8035758 | 0.89 | GSR (0.43) | CTSLCTSBCTSHCTSSCTSK | |
| Cyclohexylamine SCHEMBL8035662 | 0.87 | EPHX2 (0.36) | EPHX2CACNA1BCTSLCTSBCTSH | |
| Cyclohexylamine SCHEMBL8036004 | 0.85 | NPC1 (0.40) | KIF11GRIK1PPARGPPARA | |
| Cyclohexylamine SCHEMBL8036007 | 0.85 | NPC1 (0.40) | KIF11GRIK1PPARGPPARA | |
| Cyclohexylamine SCHEMBL8037696 | 0.80 | GRIK1 (0.41) | KIF11GRIK1CACNA1BGRIK2DPEP1 | |
| Cyclohexylamine SCHEMBL8037697 | 0.80 | GRIK1 (0.41) | KIF11GRIK1CACNA1BGRIK2DPEP1 | |
| Cyclohexylamine SCHEMBL8035558 | 0.80 | DPEP1 (0.47) | KIF11GRIK1CACNA1BGRIK2DPEP1 | |
| Cyclohexylamine SCHEMBL8035555 | 0.80 | DPEP1 (0.47) | KIF11GRIK1CACNA1BGRIK2DPEP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |