Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.67 |
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SI | P14410 | 2/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.49 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM6A | O15550 | 1/20 | 0.43 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807868 | 0.97 | TOP2A (0.72) | TOP2AMGAMGAASIMGAM2 | |
| SCHEMBL9191240 | 0.88 | TOP2A (0.58) | TOP2AMGAMGAASIMGAM2 | |
| SCHEMBL9472720 | 0.85 | TOP2A (0.77) | TOP2AGAAKDM4ENPC1RAB9A | |
| SCHEMBL31154201 | 0.82 | RAB9A (0.58) | TOP2AGAAAGPAT2KDM4ENPC1 | |
| SCHEMBL21776903 | 0.81 | NPC1 (0.48) | TOP2AGAAAGPAT2KDM4ENPC1 | |
| SCHEMBL30119890 | 0.81 | TOP2A (0.67) | TOP2AGAAKDM4ENPC1RAB9A | |
| SCHEMBL10731139 | 0.81 | TOP2A (0.55) | TOP2AGAAAGPAT2KDM4ENPC1 | |
| SCHEMBL2959863 | 0.79 | TOP2A (0.70) | TOP2AKDM4ESMN1; SMN2HSD17B10KDM6B | |
| SCHEMBL7298455 | 0.77 | CEPT1 (0.52) | TOP2AAGPAT2KDM4ENPC1RAB9A | |
| SCHEMBL12807869 | 0.77 | TOP2A (0.67) | TOP2AKDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048631-A | ALUMINUM COMPLEX; ELECTON TRANSFER, ORGANIC LUMINESCECE AND ELECTRON TRANSPORT LAYERS, THE LATER TWO STACKED BETWEEN A PAIR OF ELECTRODES; HEAT RESISTANCE, BLUISH LIGHT EMISSION, HIGH EFFICIENCY | FUTABA DENSHI KOGYO K.K. (JP) | 2000-04-11 | — | — | US | disclosed |