Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020648 | 0.94 | KDM4E (0.38) | KDM4EALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27487707 | 0.93 | KDM4E (0.35) | KDM4EALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8033942 | 0.92 | KMT2A (0.40) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8036207 | 0.90 | GRM5 (0.38) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8029983 | 0.90 | SMN1; SMN2 (0.36) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8034113 | 0.89 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL8020589 | 0.89 | SMN1; SMN2 (0.35) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8030227 | 0.89 | KMT2A (0.39) | MAPTSMN1; SMN2KMT2AMEN1PARP1 | |
| SCHEMBL8030465 | 0.88 | KMT2A (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL8020628 | 0.88 | KMT2A (0.42) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |