SCHEMBL8036247

SCHEMBL8036247

NNc1cccc(OCC(F)(F)C(F)(F)F)n1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.44
MAPK8 P45983 1/20 0.37
SCN9A Q15858 3/20 0.32
SCN5A Q14524 1/20 0.32
NUDT1 P36639 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
GRM5 P41594 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
GOT1 P17174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7221866 0.83 CYP1A2 (0.50) CNR2MAPK8MAPTCYP1A2CYP2C19
SCHEMBL8036285 0.77 CNR2 (0.45) CNR2SCN9A
SCHEMBL6342929 0.75 MAPK8 (0.61) MAPK8ALDH1A1MAPTRAB9AGRM5
SCHEMBL28390288 0.71 L3MBTL1 (0.44) CNR2MAPK8SCN5AALDH1A1GRM5
SCHEMBL14152559 0.71 CNR2 (0.58) CNR2MAPT
SCHEMBL6071585 0.69 TAAR1 (0.48) MAPK8GAAMAPTGRM5GOT1
SCHEMBL7228324 0.68 LMNA (0.46) SCN9ASCN5AMAPT
SCHEMBL23639346 0.68 MAPK8 (0.36) CNR2MAPK8ALDH1A1GRM5
SCHEMBL23781933 0.66 L3MBTL1 (0.41) CNR2SCN9ASCN5ANUDT1ALDH1A1
SCHEMBL4037970 0.65 P2RX7 (0.51) MAPK8ALDH1A1GAAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995612-A1 OPTICAL RECORDING MEDIUM AND METHOD OF PRODUCING THE SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2000-04-26 EP disclosed