Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395858 | 0.89 | FFAR1 (0.51) | FFAR1HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL7316922 | 0.84 | FFAR1 (0.52) | FFAR1HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL7321911 | 0.84 | FFAR1 (0.52) | FFAR1HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL7317620 | 0.83 | FFAR1 (0.54) | FFAR1HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL7317624 | 0.83 | FFAR1 (0.54) | FFAR1HTR1AHTR1DDRD2DRD3 | |
| SCHEMBL7397923 | 0.77 | HRH3 (0.50) | FFAR1DRD2DRD3CA2HRH3 | |
| SCHEMBL8036686 | 0.77 | HRH3 (0.60) | FFAR1DRD2DRD3HRH3MTNR1A | |
| SCHEMBL4234794 | 0.77 | HRH3 (0.49) | FFAR1DRD2DRD3CA2CA5A | |
| SCHEMBL7323697 | 0.76 | HTR1A (0.61) | HTR1AHTR1DDRD2DRD3HTR6 | |
| SCHEMBL8036667 | 0.76 | SLC6A2 (0.36) | DRD2DRD3CA2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076990-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-21 | — | — | WO | disclosed |