Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977362 | 0.90 | USP5 (0.34) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL8977367 | 0.90 | USP5 (0.34) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL8977371 | 0.90 | USP5 (0.34) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL8393131 | 0.86 | KDM1A (0.36) | HTR2AHTR2CHTR2BKDM1ACYP2D6 | |
| SCHEMBL8418649 | 0.86 | ESR2 (0.36) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL8418650 | 0.86 | ESR2 (0.36) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL29389392 | 0.82 | HTR2A (0.46) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL808710 | 0.82 | HTR2A (0.46) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL8031826 | 0.81 | — | — | |
| SCHEMBL7770328 | 0.80 | CYP3A4 (0.36) | HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718301-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| EP-0630903-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5868961-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0632044-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5679746-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0718301-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5454977-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0632044-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0630903-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |