Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977362 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8977371 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8036699 | 0.90 | HTR2A (0.38) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8015332 | 0.88 | P2RY14 (0.33) | CYP2D6KDM1ACCR2 | |
| SCHEMBL8015335 | 0.88 | P2RY14 (0.33) | CYP2D6KDM1ACCR2 | |
| SCHEMBL8015338 | 0.88 | P2RY14 (0.33) | CYP2D6KDM1ACCR2 | |
| SCHEMBL17827776 | 0.86 | HTR2A (0.42) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8418650 | 0.83 | ESR2 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8418649 | 0.83 | ESR2 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8767567 | 0.81 | HTR2A (0.39) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |