Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015335 | 0.91 | P2RY14 (0.33) | KDM1ACYP17A1CYP11B2P2RY14CYP11B1 | |
| SCHEMBL8015332 | 0.91 | P2RY14 (0.33) | KDM1ACYP17A1CYP11B2P2RY14CYP11B1 | |
| SCHEMBL8015338 | 0.91 | P2RY14 (0.33) | KDM1ACYP17A1CYP11B2P2RY14CYP11B1 | |
| SCHEMBL8036699 | 0.86 | HTR2A (0.38) | KDM1ACCR2CYP2D6CCR1HTR2A | |
| SCHEMBL8398280 | 0.86 | CYP3A4 (0.33) | P2RY14CYP3A4NPC1RAB9ACYP2C9 | |
| SCHEMBL8396919 | 0.83 | PTGS2 (0.38) | KDM1ANPC1RAB9AHTR2A | |
| SCHEMBL8393924 | 0.81 | GRM2 (0.33) | — | |
| SCHEMBL7757563 | 0.80 | CYP11B2 (0.36) | KDM1ACYP17A1CYP11B2P2RY14CYP11B1 | |
| SCHEMBL7757557 | 0.80 | CYP11B2 (0.36) | KDM1ACYP17A1CYP11B2P2RY14CYP11B1 | |
| SCHEMBL14525326 | 0.80 | HSP90AA1 (0.46) | KDM1ACYP17A1CYP11B2CYP11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |