Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036937 | 1.00 | LMNA (0.55) | LMNAGAAMAPTTDP1HPGD | |
| SCHEMBL6881641 | 0.84 | BCHE (0.52) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL6881643 | 0.84 | BCHE (0.52) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL10517767 | 0.81 | LMNA (0.61) | LMNAGAAMAPTTDP1HPGD | |
| SCHEMBL13568242 | 0.81 | LMNA (0.62) | LMNAGAAMAPTTDP1POLB | |
| SCHEMBL16400746 | 0.81 | LMNA (0.62) | LMNAGAAMAPTTDP1POLB | |
| SCHEMBL15571908 | 0.77 | ALDH1A1 (0.48) | CYP3A4HDAC2HDAC8 | |
| SCHEMBL15571905 | 0.77 | ALDH1A1 (0.48) | CYP3A4HDAC2HDAC8 | |
| SCHEMBL4960001 | 0.77 | LMNA (0.71) | LMNAGAAMAPTTDP1HPGD | |
| SCHEMBL4607313 | 0.76 | LMNA (0.71) | LMNAGAAMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988297-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE PHENYLOXIRANE COMPOUNDS | Tanabe Seiyaku Co., Ltd. (JP) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056762-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE PHENYLOXIRANE COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-17 | — | — | WO | disclosed |