Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646576 | 1.00 | LTA4H (0.47) | LTA4HS1PR1S1PR3L3MBTL1PTGDR2 | |
| SCHEMBL3895825 | 0.85 | LNPEP (0.37) | LTA4HL3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL6046896 | 0.80 | HDAC1 (0.51) | LTA4H | |
| SCHEMBL8171158 | 0.80 | GAA (0.57) | LTA4HS1PR1S1PR3KDM4EMEN1 | |
| SCHEMBL10434926 | 0.79 | CYP3A4 (0.38) | LTA4HL3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL8213428 | 0.79 | KDM4E (0.57) | LTA4HL3MBTL1KDM4ERECQLMEN1 | |
| SCHEMBL27295441 | 0.77 | KDM4E (0.57) | LTA4HKDM4EMEN1GAAKMT2A | |
| SCHEMBL27295439 | 0.77 | KDM4E (0.57) | LTA4HKDM4EMEN1GAAKMT2A | |
| SCHEMBL3954076 | 0.76 | LTA4H (0.67) | LTA4HS1PR1S1PR3SLC1A3SLC1A2 | |
| SCHEMBL2309395 | 0.76 | LTA4H (0.67) | LTA4HS1PR1S1PR3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547342-B1 | Method for crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester | AJINOMOTO KK (JP) | 2000-04-05 | — | — | EP | claimed |
| EP-0751146-A1 | Crystallization of alpha-L-aspartyl-l-phenylalanine methyl ester from aqueous solution | HOLLAND SWEETENER COMPANY V.O.F. (NL) | 1997-01-02 | — | — | EP | disclosed |
| WO-1991013860-A1 | METHOD FOR INCREASING THE ALPHA TO BETA RATIO IN AN ASPARTAME COUPLING REACTION | THE NUTRASWEET COMPANY (US) | 1991-09-19 | — | — | WO | disclosed |
| US-4071615-A | DIPEPTIDE SWEETENER | COLGATE PALMOLIVE COMPANY (US) | 1978-01-31 | — | — | US | disclosed |