Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13225385 | 1.00 | TSHR (0.42) | TSHRTLR2TLR1SMN1; SMN2HPGD | |
| SCHEMBL29467640 | 1.00 | TSHR (0.42) | TSHRTLR2TLR1SMN1; SMN2HPGD | |
| SCHEMBL30748709 | 0.90 | TSHR (0.53) | TSHRTLR2TLR1SMN1; SMN2HPGD | |
| SCHEMBL14117979 | 0.89 | TSHR (0.47) | TSHRTLR2TLR1SMN1; SMN2HPGD | |
| SCHEMBL25330597 | 0.88 | TLR2 (0.41) | TSHRTLR2TLR1SMN1; SMN2MEN1 | |
| SCHEMBL25933067 | 0.88 | TLR2 (0.39) | TSHRTLR2TLR1MEN1KMT2A | |
| SCHEMBL25933066 | 0.88 | TLR2 (0.39) | TLR2TLR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25933059 | 0.88 | TLR2 (0.39) | TSHRTLR2TLR1MEN1KMT2A | |
| SCHEMBL21611677 | 0.88 | TLR2 (0.41) | TSHRTLR2TLR1SMN1; SMN2MEN1 | |
| SCHEMBL22388928 | 0.87 | TLR2 (0.38) | TSHRTLR2TLR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987197-B2 | Protease stabilized, pegylated insulin analogues and uses thereof | NOVO NORDISK A/S (DK) | 2015-03-24 | — | — | US | disclosed |
| US-20120071402-A1 | Protease Stabilized, Pegylated Insulin Analogues | NOVO NORDISK A/S (DK) | 2012-03-22 | — | — | US | disclosed |
| US-20110319591-A1 | PEGYLATED, EXTENDED INSULINS | NOVO NORDISK A/S (DK) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319591-A1 | PEGYLATED, EXTENDED INSULINS | IAPP, IGF1R, INSR | TSHR 576/4885TLR2 2948/4885TLR1 1650/4885 |
| US-20120071402-A1 | Protease Stabilized, Pegylated Insulin Analogues | IDE, IAPP, IGFBP4 | TSHR 656/4885TLR2 3842/4885TLR1 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.