SCHEMBL8037533 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	EPHX2	P34913	2/20	0.40

▸	NAAA	Q02083	2/20	0.36

▸	MLYCD	O95822	1/20	0.36

▸	EPHX1	P07099	6/20	0.35

▸	ASAH1	Q13510	1/20	0.34

▸	NR5A2	O00482	1/20	0.34

▸	NR5A1	Q13285	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	GPR84	Q9NQS5	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8041445	0.90	EPHX2 (0.41)	EPHX2NAAAMLYCDEPHX1ASAH1
SCHEMBL8035781	0.90	EPHX2 (0.41)	EPHX2NAAAMLYCDEPHX1ASAH1
SCHEMBL8034781	0.88	HPGD (0.36)	ALDH1A1HPGD
SCHEMBL8034312	0.79	TBXA2R (0.38)	EPHX2
SCHEMBL8038463	0.78	EPHX2 (0.39)	EPHX2
SCHEMBL8036201	0.78	EPHX2 (0.39)	EPHX2
SCHEMBL8041408	0.76	SMN1; SMN2 (0.32)	ALDH1A1HPGD
SCHEMBL8035784	0.74	EPHX1 (0.40)	EPHX2NAAAEPHX1
SCHEMBL8037862	0.72	CYP3A4 (0.38)	ALDH1A1
SCHEMBL8025618	0.70	COMT (0.40)	EPHX1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009081892-A1	NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE	KISSEI PHARMACEUTICAL CO., LTD. (JP)	2009-07-02	—	—	WO	disclosed