Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023142 | 0.89 | ALDH1A1 (0.39) | SMN1; SMN2POLBHPGDALDH1A1MEN1 | |
| SCHEMBL8034781 | 0.85 | HPGD (0.36) | SMN1; SMN2POLBHPGDALDH1A1KMT2A | |
| SCHEMBL8041445 | 0.85 | EPHX2 (0.41) | — | |
| SCHEMBL8035781 | 0.85 | EPHX2 (0.41) | — | |
| SCHEMBL8037015 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2POLBHPGDALDH1A1MEN1 | |
| SCHEMBL8038899 | 0.78 | PPIA (0.52) | POLBHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8034312 | 0.77 | TBXA2R (0.38) | — | |
| SCHEMBL8037533 | 0.76 | EPHX2 (0.40) | HPGDALDH1A1 | |
| SCHEMBL8036201 | 0.76 | EPHX2 (0.39) | — | |
| SCHEMBL8038463 | 0.76 | EPHX2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |