Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8035468 | 0.96 | ALOX5 (0.33) | ALOX5SLC6A3 | |
| SCHEMBL8033249 | 0.88 | — | — | |
| SCHEMBL8039777 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL8037563 | 0.76 | ALOX5 (0.33) | ALOX5SLC6A3 | |
| Bromide SCHEMBL8035475 | 0.76 | ALOX5 (0.33) | ALOX5SLC6A3 | |
| SCHEMBL11151827 | 0.73 | — | — | |
| SCHEMBL8039775 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8032877 | 0.68 | SLC6A3 (0.31) | SLC6A3SLC6A4 | |
| SCHEMBL599517 | 0.67 | PDE2A (0.32) | ALOX5 | |
| Hydrochloric Acid SCHEMBL8032887 | 0.67 | ALOX5 (0.31) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022822-A | Organotin compound and catalyst for transesterification comprising the same | RYOJI NOYORI (JP) | 2000-02-08 | — | — | US | disclosed |