Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.72 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535196 | 0.82 | PPARG (0.72) | PPARGRORC | |
| SCHEMBL8035508 | 0.81 | PPARG (1.00) | PPARGRORC | |
| SCHEMBL8037681 | 0.81 | PPARG (1.00) | PPARGRORC | |
| SCHEMBL4564570 | 0.80 | PPARG (1.00) | PPARG | |
| SCHEMBL8035491 | 0.80 | PPARG (1.00) | PPARG | |
| SCHEMBL8045639 | 0.80 | PPARG (1.00) | PPARG | |
| SCHEMBL4532827 | 0.79 | PPARG (0.68) | PPARGRORCHDAC1HDAC6 | |
| SCHEMBL8042319 | 0.77 | PPARG (0.79) | PPARG | |
| SCHEMBL3040156 | 0.76 | IMPDH2 (0.54) | — | |
| SCHEMBL8024565 | 0.75 | PPARG (0.87) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |