SCHEMBL8037839

SCHEMBL8037839

CCCOC(=O)c1ooc1C(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8039535 0.87 ALDH1A1 (0.47) ALDH1A1LMNAESR1TSHRRAB9A
SCHEMBL8039509 0.86 ALDH1A1 (0.40) ALDH1A1LMNAESR1CHRM1TSHR
SCHEMBL8041041 0.85 IGF1R (0.42) TSHRRAB9A
SCHEMBL8039496 0.82 CYP2C9 (0.40)
SCHEMBL8037479 0.77 TSHR (0.42) ALDH1A1LMNAESR1TSHRTDP1
SCHEMBL18589824 0.75 ALDH1A1 (0.66) ALDH1A1LMNAESR1CHRM1TSHR
SCHEMBL4345814 0.75 CYP2C9 (0.40) ALDH1A1TSHRTDP1
SCHEMBL8037889 0.75 DGAT1 (0.40) ALDH1A1LMNATSHR
SCHEMBL28994382 0.72 ALDH1A1 (0.77) ALDH1A1LMNATSHRTDP1
Acetone SCHEMBL12471978 0.72 CYP2C9 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127325-A GRAFT COPOLYMER OF AN OIL-SOLUBLE OLEFIN POLYMER AND OF A COPOLYMER (B) OF A MONOMER HAVING A PEROXIDE BOND WITH (METH)ACRYLATE; OR COPOLYMER (C) OF A PEROXIDE CONTAINING MONOMER AND SPECIFIED MONOMERS; NO PHASE SEPARATION NOF CORPORATION (JP) 2000-10-03 US disclosed
EP-0872539-A1 VISCOSITY INDEX IMPROVER, PROCESS FOR PREPARING THE SAME AND LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 1998-10-21 EP disclosed