Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345814 | 0.96 | CYP2C9 (0.40) | CYP2C9CYP2C19NPSR1MEN1KMT2A | |
| SCHEMBL8039496 | 0.87 | CYP2C9 (0.40) | CYP2C9CYP2C19NPSR1ACHETP53 | |
| SCHEMBL8037889 | 0.79 | DGAT1 (0.40) | CYP2C9CYP2C19NPSR1KMT2AACHE | |
| SCHEMBL8027510 | 0.73 | MAPT (0.45) | CYP2C9CYP2C19NPSR1KMT2ACYP1A2 | |
| SCHEMBL8037839 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL8040978 | 0.68 | SMN1; SMN2 (0.43) | NPSR1MEN1KMT2ATP53MAPT | |
| SCHEMBL27093606 | 0.68 | CYP2C9 (0.41) | CYP2C9CYP2C19NPSR1MEN1KMT2A | |
| SCHEMBL16272968 | 0.68 | CYP2C9 (0.37) | CYP2C9CYP2C19NPSR1MEN1KMT2A | |
| SCHEMBL6580237 | 0.67 | GRM6 (0.40) | CYP2C9CYP2C19NPSR1SLC7A5HSD17B10 | |
| SCHEMBL27718695 | 0.67 | TDP1 (0.36) | MEN1KMT2ATP53MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670388-A2 | METHOD OF MAKING OPHTHALMIC DEVICES AND COMPONENTS THEREOF FROM HYDROPHOBIC ACRYLIC (HA) POLYMERS WITH REDUCED OR ELIMINATED GLISTENINGS | Key Medical Technologies, Inc. (US) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012106118-A2 | METHOD OF MAKING OPHTHALMIC DEVICES AND COMPONENTS THEREOF FROM HYDROPHOBIC ACRYLIC (HA) POLYMERS WITH REDUCED OR ELIMINATED GLISTENINGS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2012-08-09 | — | — | WO | disclosed |