Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039699 | 0.88 | TSHR (0.58) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL8041190 | 0.87 | TSHR (0.53) | TSHRSMN1; SMN2TDP1CYP1A2CYP2C19 | |
| SCHEMBL8037877 | 0.86 | TSHR (0.59) | TSHRSMN1; SMN2TDP1CYP1A2CYP2C19 | |
| SCHEMBL8041262 | 0.86 | TSHR (0.64) | TSHRSMN1; SMN2TDP1CYP1A2ALDH1A1 | |
| SCHEMBL8039720 | 0.85 | TSHR (0.67) | TSHRSMN1; SMN2TDP1CYP1A2ALDH1A1 | |
| SCHEMBL8038282 | 0.82 | PLK1 (0.50) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL8037888 | 0.78 | TSHR (0.55) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL8044213 | 0.78 | MEN1 (0.50) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL8037924 | 0.78 | TSHR (0.54) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL8041066 | 0.78 | TSHR (0.54) | TSHRSMN1; SMN2TDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |