Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037897 | 0.90 | CTSV (0.52) | LMNASMN1; SMN2NPC1RAB9ALTA4H | |
| SCHEMBL8037867 | 0.88 | TSHR (0.57) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8041262 | 0.87 | TSHR (0.64) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8027769 | 0.86 | ALDH1A1 (0.53) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8039720 | 0.86 | TSHR (0.67) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8037877 | 0.85 | TSHR (0.59) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8041190 | 0.84 | TSHR (0.53) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8044221 | 0.83 | MAPT (0.55) | TSHRTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8027785 | 0.81 | MRGPRX4 (0.48) | TSHRTDP1KDM4ESMN1; SMN2LTA4H | |
| SCHEMBL8041209 | 0.81 | LNPEP (0.44) | TSHRTDP1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-5808144-A | ANTIALLERGENS | TEIJIN LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0806412-A1 | BENZENE DERIVATIVES | TEIJIN LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |