Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037897 | 0.89 | CTSV (0.52) | KMT2AMEN1HCAR2SMN1; SMN2NPC1 | |
| SCHEMBL8027750 | 0.89 | PLK1 (0.45) | PLK1KMT2AMEN1HCAR2SMN1; SMN2 | |
| SCHEMBL8041218 | 0.87 | MEN1 (0.49) | PLK1KMT2AMEN1HCAR2SMN1; SMN2 | |
| SCHEMBL8044213 | 0.85 | MEN1 (0.50) | PLK1KMT2AMEN1HCAR2SMN1; SMN2 | |
| SCHEMBL8027746 | 0.85 | ALDH1A1 (0.55) | KMT2AMEN1HCAR2SMN1; SMN2NPC1 | |
| SCHEMBL8039700 | 0.84 | ALDH1A1 (0.49) | PLK1KMT2AMEN1HCAR2SMN1; SMN2 | |
| SCHEMBL8037867 | 0.82 | TSHR (0.57) | PLK1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8038287 | 0.82 | FNTA (0.52) | KMT2AMEN1HCAR2SMN1; SMN2NPC1 | |
| SCHEMBL8041190 | 0.79 | TSHR (0.53) | KMT2ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL8039687 | 0.79 | SRD5A1 (0.43) | KMT2AMEN1ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |