Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039700 | 0.91 | ALDH1A1 (0.49) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8041262 | 0.88 | TSHR (0.64) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8039720 | 0.87 | TSHR (0.67) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8037867 | 0.86 | TSHR (0.57) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8039699 | 0.85 | TSHR (0.58) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8041190 | 0.81 | TSHR (0.53) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL10340241 | 0.81 | GAA (0.59) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8037888 | 0.80 | TSHR (0.55) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8037924 | 0.79 | TSHR (0.54) | TSHRTDP1ALDH1A1MAPK1GAA | |
| SCHEMBL8041066 | 0.79 | TSHR (0.54) | TSHRTDP1ALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |