Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038298 | 1.00 | DRD2 (0.49) | DRD2LSSSLC2A1HTR3ASRD5A1 | |
| SCHEMBL8014280 | 0.96 | DRD2 (0.46) | DRD2LSSSLC2A1HTR3ASRD5A1 | |
| SCHEMBL8014285 | 0.96 | DRD2 (0.46) | DRD2LSSSLC2A1HTR3ASRD5A1 | |
| SCHEMBL8076440 | 0.91 | DRD2 (0.54) | DRD2LSSSLC2A1HTR3ASRD5A1 | |
| SCHEMBL8076438 | 0.91 | DRD2 (0.54) | DRD2LSSSLC2A1HTR3ASRD5A1 | |
| SCHEMBL8040067 | 0.90 | DRD2 (0.46) | DRD2LSSSLC2A1HTR3ASPHK1 | |
| SCHEMBL8040070 | 0.90 | DRD2 (0.46) | DRD2LSSSLC2A1HTR3ASPHK1 | |
| SCHEMBL9008439 | 0.89 | DRD2 (0.44) | DRD2LSSSLC2A1HTR3ASPHK1 | |
| SCHEMBL8400111 | 0.85 | SPHK1 (0.33) | DRD2MEN1KMT2ASLC6A3MAPT | |
| SCHEMBL8036209 | 0.85 | SPHK1 (0.33) | DRD2MEN1KMT2ASLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687678-B1 | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5693841-A | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0765880-A1 | Process for preparing sil acyclohexane-based liquid crystal compounds from silacyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0687678-A1 | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |